![]() Food and Drug Administration (FDA) in the last decade. Several agents have received approval from the U.S. Molecular targeted therapy is a new approach to cancer treatment. rituximab and trastuzumab were approved during the late 1990s to treat lymphoma and breast cancer, respectively. With an increased understanding of the biology of cancer, there are now several therapeutic monoclonal antibodies available. This work was a stepping stone to a new era of hormone therapy, with the introduction of drugs like tamoxifen and anastrozole, etc. Charles Huggins won a Nobel Prize in 1966 for investigations on hormone therapy in prostate cancer. studied the association of translocation of chromosomes 9 and 22 to several leukemias, which later led to developing the first molecular targeted treatments years later (imatinib). And drugs like thiopurines (e.g., 6-mercaptopurine), 5-fluorouracil came into the forefront of cancer treatment. The successful management of choriocarcinoma and leukemias with methotrexate led to further investigations in cancer chemotherapy. Farber et al., in 1947, showed success in the treatment of childhood leukemia by using antimetabolites with antifolate activity, called aminopterin, later be known as methotrexate. The discovery of actinomycin D pioneered the search for more antitumor antibiotics, including anthracyclines, mitomycin, and bleomycin. Publication of the Lindskog article suggesting the success of nitrogen mustard in the treatment of lymphoma had a considerable initial effect on the development of cancer chemotherapy, including oral derivatives like chlorambucil and ultimately cyclophosphamide. As micrometastases and recurrence of cancer after surgery and radiation therapy became evident, combination chemotherapy started gaining significance. Radiotherapy ad surgery were the mainstays of cancer management in the 1960s. Historical documents suggest the use of arsenicals started in the 1900s. He was also the first scientist to study animal models to screen a series of chemicals regarding their potential activity against diseases. The term “chemotherapy” was coined by German chemist Paul Ehrlich who investigated the use of drugs to treat infectious diseases. The three events that led to the development of cancer treatment began with three events in the last century: the discovery of X-rays by Wilhelm Konrad Roentgen, the use of transplantable animal-tumor models in cancer research, and the first surgical procedure developed by Halsted (radical mastectomy).
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![]() There are four additional Ethernet ports on the back, and the Wi-Fi can reach speeds of 3 Gbps. What you’ll love: Compatible with DOCSIS technology, the modem can easily handle combined download speeds of 6.5 Gbps. ![]() What you need to know: This cable modem is an excellent all-in-one solution as it has a built-in Wi-Fi transmitter and a super-fast 2.6-gigabit per second Ethernet port. What’s the best Arris modem to buy? Top Arris modem Buying an Arris modem ensures that you get the latest connectivity technology - and you get to keep it. Also, when you cancel your service, you usually have to return the modem. The default modem that comes with your internet package is usually not good enough, especially after a few years. Why would you want to buy an Arris modem?Ī. This is a standard used by cable providers for the highest internet speeds. Any Arris modem labeled this way uses Data Over Cable Service Interface Specification technology. Arris modem FAQ Why are some modems labeled as DOCSIS?Ī. An entry-level cable modem that doesn’t have built-in Wi-Fi costs $80-$90, while a Wi-Fi and modem combination costs $150-$250. The price depends on the modem’s technology and additional functions. How much you can expect to spend on an Arris modem All Arris Surfboard modems are compatible with the Manager App where you can keep track of connected devices, enable parental controls and test the speed of your Wi-Fi. It’s far more convenient if you have a mobile app at your fingertips to quickly see what the problem is. When something doesn’t seem right, you don’t want to sit in front of a computer diagnosing the problem. For example, the G36 has one port of 2.5 gigabits per second and four ports capable of 1 gigabit per second. So look for a modem that has at least two Ethernet ports compatible with your internet connection’s speed. Often you also find that internet speeds are much faster over an Ethernet cable than through Wi-Fi. A good-quality Arris modem has multiple ports so you can hard-wire a gaming console, computer or smart TV to the connection. Wi-Fi can notoriously be spotty sometimes, and the best way around that is an Ethernet cable. A good-quality Arris modem comes with detailed instructions on how to set it up, where to place it for optimum coverage and which additional equipment you may need. ![]() The last thing you want to do when you get a new modem is to struggle. What to look for in a quality Arris modem Easy setup Getting a modem that accommodates faster speeds than your connection is much better than getting a modem that can only handle half of that. It’s great when you go for the fastest available technology, but not only does the modem need to be compatible with your ISP, it also needs to be in line with your expected internet speed. If you already have a good-quality Wi-Fi router, an Arris cable modem can improve the speeds your ISP supplies. The cable connection comes in, and the Wi-Fi pushes it to mobile devices. An Arris cable and Wi-Fi combination replaces your current setup by having two devices built into one gadget. These often don’t have Wi-Fi capabilities or are woefully inadequate. The best option is a cable and Wi-Fi combinationĭepending on your home setup, you probably received a modem with your connection. Whether a modem will work depends on the speed and technology used by the ISP. For example, the SB82000 is compatible with 17 ISPs while the T25 is only compatible with one provider. Unlike other routers or traditional Wi-Fi devices, you must ensure that you get an Arris modem compatible with your internet service provider. What to know before you buy an Arris modem Ensure that it’s compatible You simply attach your cable connection to the modem, and the built-in Wi-Fi function spreads the signal throughout your home. ![]() This is where an Arris modem, such as the Arris Surfboard G36 Multi-Gigabit Cable Modem and Wi-Fi Router, can make all the difference. The routers and access points your provider supplies are often inadequate, leading to dead Wi-Fi coverage or slow download speeds. There are plenty of options when it comes to internet connections, but you don’t have to use the default hardware bundled with your subscription. ![]() ![]() I prefer games with an auto-attack function, or at least a method to stop you reducing your mouse and keyboard to splinters of plastic from hammering them to holy-hell.ĭungeon Blitz can be played either solo or in groups, but Blue Mammoth admits that the game really opens up when you play it socially. Most of the time combat was nothing more than hitting left mouse button enough times to build up your mana bar enough to use a special attack, which never really felt all that special, then back to the button bashing. There are often many enemies on the screen at once and combat devolves into a button-bushing exercise. It’s not a game in itself and you wouldn’t log on just to craft or make money, real or virtual.Ĭombat reminds me of Diablo II. ![]() There’s a small crafting area as well, that let’s you craft various potions and bits of equipment, but like the rest of the game this is casual crafting designed to embellish the game. The gameplay of Dungeon Blitz is not mould breaking but it doesn’t really need to be. You kill things, you get loot, you kill more things, defeat the dungeon boss, leave and buy new things, skill up etc. “Īnyway, you pick up quests which will invariably have you disappearing into little instanced dungeons. Is it just me or does a disproportionate amount of games these days go with the glowing exclamation mark/question mark thing. “I wish that games would think of other ways to show people have quests. People show that they have quests by way of a glowing exclamation mark’s above their head. Then you hit dry land and are directed to go to a village, well a few houses with some trainers, shops and few stereotypical NPC’s hanging around. In the tutorial a talking parrot tells you all about that stuff, you fight off a few goblins, a few goop-shooting bats and a giant purple octopus, nothing to strenuous. Special attacks are performed by clicking on the action bar or pressing the required shortcut key. W,A,S,D cause your character to jump, run left, drop a level, run right respectively, while left mouse button uses your basic attack. A brief introduction to the game and the controls, and the controls for Dungeon Blitz are easy. Future visits to the site seem to remember those details I’ve never had to login again anyway.Īs with all games these days, the first part of the game is the tutorial. Which wasn’t a ball-ache, I just needed to enter a login name and password. Once you have created your character, in my case a mage, you are asked to create your account. The rest of the character creation is rather basic, you have a few different hairstyles and faces you’re able to change the colour of a few things, but the characters remain very similar to each other, although there is enough different between the classes to compensate for most of that. As soon as you access the site you’re straight into character creation and asked to choose your class out of the three available (Paladin, Rogue or Mage). There isn’t a lengthy login or account creation process to go through. My gaming time is becoming more scarce and much more precious, so is it good enough to make me want to find some time for it?ĭungeon Blitz is an internet browser game, there’s nothing to download at all and it’s very easy to start playing. This post here, in fact, but it would be rather amiss of me if I didn’t play it and let you know what I think about it, which is exactly what I did. I was asked to let you all know that Blue Mammoth have released a browser-based MMO called Dungeon Blitz. We concluded that individuals, if given the opportunity, seek to promote “positive assortment” for Self’s phenotype, especially when the level of similarity approaches an optimal point that is similar to Self without causing a conscious acknowledgment of the similarity.Ĭurrent psychological research on human attractiveness has replaced the relativistic belief that “beauty is in the eye of the beholder” with a universalistic one. A forced-choice signal-detection paradigm showed that the effect of self-resemblance operated at an unconscious level, since the same participants were unable to detect the presence of their own faces in the above morphs. 33%) of another face, the 22% was chosen consistently as the preferred morph and, in particular, when Self was blended in the partner’s face. When ranking morphs differing in level of amalgamation (i.e., 11% vs. The Self-based morph was also preferred to the morph of their partner’s face blended with the partner’s same-sex “prototype”, although the latter face was (“objectively”) judged more attractive by other individuals. Participants distinctly preferred a “Self-based morph” (i.e., their partner’s face with a small amount of Self’s face blended into it) to other morphed images. ![]() Participants chose the most attractive face image of their romantic partner among several variants, where the faces were morphed so as to include only 22% of another face. In the present study, we assessed the role of resemblance to Self’s facial traits in judgments of physical attractiveness. Thus, mate choice may be a balancing of phenotypic similarity and dissimilarity between partners. Opposing forces influence assortative mating so that one seeks a similar mate while at the same time avoiding inbreeding with close relatives. CBS will broadcast the game between the Tampa Bay Buccaneers and the Kansas City Chiefs. The Super Bowl LV will take place on February 7, 2021, at Raymond James Stadium in Tampa, Florida. He will take the stage at around 8:30 p.m. Furthermore, actor and comedian Tiffany Haddish is hosting the event.įurthermore, popular artist The Weeknd will be playing the halftime show. The Verizon-sponsored event includes performances by Brandi Carlile, Miley Cyrus, Alicia Keys, Christina Aguilera, H.E.R., and Brittany Howard. The two country music stars aren’t the only singers who will be performing during the concert. The proceeds of the event will help raise funds for small businesses that are still struggling because of the COVID-19 pandemic. The event will be held as a live-stream concert, called The Big Concert for Small Business. In addition to performing “The Star-Spangled Banner,” Church and fellow country music star Luke Bryan will be performing at the Super Bowl LV after party show. Eric Church, Luke Bryan Performing After Party Show ![]() They also follow on the heels of last year’s national anthem singer, Demi Lovato. Their performance will follow in the footsteps of Aretha Franklin and Aaron Neville in 2006. However, the two will blend their styles together in what will be only the second national anthem duet in Super Bowl history. Vikings game.Church and the 33-year-old Sullivan have never performed together. In 2010, skipping vocal duties, hotshot guitarist Malina Moye won plaudits for doing a Hendrix-style instrumental version of the national anthem, thought to be the first at a pro game by a Black woman playing guitar, before a Cowboys vs. was not the first woman to go loud with a guitar in an NFL pre-show. She currently has five nominations for the upcoming Grammy Awards, for her songs “I Can’t Breathe” and “Better Than I Imagined.” is about to be represented on screens with “Fight for You,” her closing theme for “Judas and the Black Messiah,” which is being touted as an Oscar contender. Sullivan released her first album since 2015, “ Heaux Tales,” in January it debuted at No. Such was the case for Eric Church, who received a text from fellow country star and friend Luke Bryan, after his rousing rendition of 'The Star-Spangled Banner' at Super Bowl LV on February 7. Country artist Eric Church and R&B singer Jazmine Sullivan come together for a performance of the National Anthem at Super Bowl 2021. His newest single, “Hell of a View,” just entered the top 20 on the Mediabase country chart. Coliseum, had been widely seen since it premiered in conjunction with another NFL game four months ago.Ĭhurch is set to release three new albums - individually titled “Heart,” “&” and “Soul” - in April. The pre-telecast also featured Alicia Keys singing the Black anthem “Lift Every Voice,” but that taped performance, filmed at the L.A. However the game turns out, one win was already on the boards. After he sang the first few lines alone, Sullivan essentially took over, with Church staying in his comfortable lower range as a harmony vocalist - even when the song further took off with a key change nearing the climax. ![]() But her presence saved him the need to soar into a high range he doesn’t have. How their extremely different voices would meld was a subject of suspense - even to the stars themselves, possibly, as Church recently admitted he hadn’t met Sullivan yet, weeks after being announced as her duet partner. That didn’t turn out to be the only extraordinary thing about their rendition: it was certainly one of the few significant syncopated versions of “The Star Spangled Banner” in TV history, with Church gently strumming the song on his electric guitar with light, funky accents on the 2s and the 4s, before Sullivan took it into an entirely more soulful realm. Country and R&B stars Eric Church and Jazmine Sullivan teamed up Sunday for one of the more unusual wrinkles in Super Bowl national anthem history, and something Frances Scott Key probably scarcely imagined: a duet. ![]() However the name actually traces its origins to a village in Higo province where the original founder of this sword making style, Oyama Kozuke no Suke, was born and operated his forge from. can literally bisect someone clean in half). The name Dotanuki is often translated as a 'torso cutter' (i.e. These were no nonsense blades favored by battle hardened warrior during the turbulent and endless civil wars of the Sengoku Jidai, and in peace time had such a viscous reputation for raw cutting power that they were eventually outlawed under the Tokugawa Shogunate. Historical European Martial Arts (HEMA).Ultra Durable 'Beater' Katana under $400.Affordable Traditional Blades with 'Hamon'. ![]() Patreon / Ko-Fi / PayPal / Support The Rolistes via your purchasesĭrivethruRPG / Dungeon Masters Guild / Itch. Contact The RPG AcademyĮmail: Facebook / Website Support The Rolistes financially Please consider contributing to my Patreon, making a modest donation via Paypal or even support your show at no extra cost via your purchases on DriveThru RPG. The RPG Academy Film Studies is licensed under Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License. See you later for more silver screen extravaganza.ĭownload the episode, listen, rate or review the show on Podchaser, Apple Podcasts, Spotify, or Stitcher. In the meantime make sure to check Alex Roberts’ Patreon and to pre-order Brinkwood: The Blood of Tyrants!Īlex has not created a “For The Blade” hack of “ For the Queen” yet but feel free to tweet to encourage the creation of one. You’ll have to wait to find out which movie the next episode will be about. We got plenty of new Film Studies already recorded but we are not quite sure which one will be edited and released first. “ Dragon Age RPG” by Green Ronin Publishing.“ Vampire The Masquerade” by White Wolf.“ Masks: A New Generation” by Brendan Conway for Magpie Games.“ Dudes of Legend: How To Be Fucking Awesome” by Chuck Wendig for White Wolf.“ Night’s Black Agents: Solo Ops” by Pelgrane Press.“ Katanas & Trenchcoats” by Ryan Macklin.“ Fate Core System” by Evil Hat Productions.“ Savage Worlds” by Shane Lacy Hensley for Pinnacle Entertainment.“ GURPS” by Steve Jackson, Sean Punch and David Pulver for Steve Jackson Games.“ Star Crossed“, “ For The Queen“, “ Precious Little Animals” by Alex Roberts.“ Brinkwood: Blood of Tyrants” by Erik Bernhardt for Crone RPG.Mentioned tabletop RPG settings and systems: Erik Bernhardt aka Erik the Bearik, author of the vampire-themed “ Brinkwood: Blood of Tyrants“.Īs usual, we review this film and discuss ways it could inspire tabletop RPG adventures, characters or practices.Alex Roberts, author of “ Star Crossed“, “ For The Queen” and “ Precious Little Animals” as well as host of Backstory Podcast.Here’s “Blade”, the famous trench coat and katana Wesley Snipes vehicle from 1998 directed by Stephen Norrington.įor this journey to the darkest corners of Los Angeles, Kalum is joined by: You can alsoĭon’t forget to join our newsletterif you don’t want to miss any of our content.Īfter an episode of Film Studies helmed by Michael himself, Kalum takes us to a Marvel movie well before the advent of the MCU. ![]() Download the episode, listen, subscribe & review on Apple Podcasts, Spotify or Podchaser. Twelve men were arrested for patronizing a prostitute and four Wyandanch women were arraigned on prostitution counts. Town of Brookhaven fire marshals and building inspectors also issued a number of citations for town code violations.Įarlier in the month, 16 area residents were arrested during a three-day sting between September 3-5 in the North Babylon and Wyandanch area. No matter what you're looking for, you can find it in the Long Island Backpage Classifieds From used cars, to garage sale listings, professional. On September 24 Suffolk County's Sixth Precinct raided the Jasmine Massage Parlor in Centereach arresting five Asian women (all from Flushing, Queens), and one Selden man. Backpage Long Island New York Classifieds. Four Asian females were arrested and charged with assorted prostitution counts. In fact the advertised piano store was a front for a massage parlor. Temporarily disable your anti-virus or firewall running in background. Clear internet cookies and browser cache. Meanwhile, a three-week investigation by the Suffolk County Police culminated in the September 19 raid on The Piano Gallery in Huntington Station. Step 2: Switch off your modem and after restarting your computer turn it on again. Stings in Wyandanch on September 17 resulted in the arrest of nine individuals while another nine Long Islanders were apprehended during a September 20 undercover operation in North Amityville. Another September 19 "John Sting" was conducted in Wyandanch netting nine arrests. ![]() We offer a variety of care services, tailored to. Our staff is experienced in every level of care, including accident rehabilitation, post-hospital convalescence, illness, and short- and long-term disability. ![]() ![]() Bay Shore's "Sunnybrook" area saw the greatest amount of arrests, 18, during a September 19 sting. Utopia Home Care pledges to treat every client with compassion and dignity, and to help them achieve as much independence as possible. Listing by Modern Spaces (47 42 Vernon Boulevard, Long Island City, NY 11101). A total of 53 individuals were arrested in the eight days between September 17-24 for prostitution-related crimes.įour separate "John Stings" netted 43 arrests while raids on two massage parlors resulted in another 10 arrests. 65-18 Utopia Parkway: Real Estate, school zoning and more information. The world's oldest profession may still be a tantalizing alternative for some, but putting the kabosh on illicit sexual entrepreneurs has kept the Suffolk County Police Department on maximum overload in recent weeks. |
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